The University will soon release a tender for an LC-MS system to perform Single Cell Proteomics (SCP).

The University is looking to purchase a dedicated high-throughput LC-MS system for SCP analysis at the University of Sydney. It will be installed in the Sydney Mass Spectrometry laboratories at the Charles Perkins Centre. The system will have best-in-class performance for SCP workflows from sample preparation through to data analysis. It will be used to train students as well as to support many researchers, research initiatives and industry partners.

Some mandatory requirements of this tender are:

1. Participant must have an existing installed base of SCP-capable LC-MS systems in research-focused laboratories in either academic, or industrial settings.

2. Participant must have existing trained support engineers and a service department able to support the system that will be located in Sydney, Australia.

3. The threshold for acceptable performance for SCP is the reproducible (CVs ( 20%) identification of )3000 proteins per HeLa cell when analysing >40 cells per day using label-free quantification (i.e. without the use of stable isotope labels). Innovations that allow for a significantly higher number of protein identifications per cell would be advantageous.

4. A well-integrated sample preparation, LC separation, data collection and data analysis pipeline

PROJECT TIMING

The tender will be released during the last week of March 2025 and be open for 3 weeks

REGISTRATION IS REQUIRED

If you meet all the mandatory requirements listed above and are interested in registering for this tender, please follow the Supplier Registration Guidance attached to this notice.